sábado, 10 de setembro de 2011

What's new for 'fibromyalgia' in PubMed

This message contains My NCBI what's new results from the National Center for Biotechnology
Sender's message: Search: fibromyalgia
Sent on Saturday, 2011 Sep 10
Search fibromyalgia
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PubMed Results

1.Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia.

Smith SB, Maixner DW, Fillingim RB, Slade G, Gracely RH, Ambrose K, Zaykin DV, Hyde C, John S, Tan K, Maixner W, Diatchenko L.

Arthritis Rheum. 2011 Sep 8. doi: 10.1002/art.33338. [Epub ahead of print]

PMID: 21905019 [PubMed - as supplied by publisher]
Comment: this breakthrough study reveals gene candidates for causing fibromyalgia - interstingly most of them relates somewhat to descending pain control that occurs in supraspinal neural centers, highlighting the critical importance of this phenomenon to fibromyalgia (comment added by the blogger).
2.Association of fibromyalgia characteristics in patients with non-metastatic breast cancer and the protective role of resilience.

Schrier M, Amital D, Arnson Y, Rubinow A, Altaman A, Nissenabaum B, Amital H.

Rheumatol Int. 2011 Sep 8. [Epub ahead of print]

PMID: 21901352 [PubMed - as supplied by publisher]
3.Psychological distress in fibromyalgia patients: A role for Catechol-O-Methyl-Transferase Val158Met polymorphism.

Desmeules J, Piguet V, Besson M, Chabert J, Rapiti E, Rebsamen M, Rossier MF, Curtin F, Dayer P, Cedraschi C.

Health Psychol. 2011 Sep 5. [Epub ahead of print]

PMID: 21895373 [PubMed - as supplied by publisher]

Comment: fibromyalgia is now recognized as a disease with a molecular background that has been explored in the last few years. One can say that it is a disease with a pain modulation, processing and perception alteration that leads to chronic pain. Cathecolaminergic signaling is central to its pathogenesis and this is the basis of the most used pharmacological treatments used in the last years. The author of this blog has published commentaries and reviews about this topic in peer-reviewed journals. You can check this following the link to my CV: http://bit.ly/oH8Bfu

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